Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.
N-Acetyl Selank Amidate - 10mg
Out of stock
What is N-Acetyl Selank Amidate?
N-Acetyl Selank Amidate is a chemically modified analog of the synthetic heptapeptide Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro), itself derived from the endogenous immunomodulatory peptide tuftsin. The compound incorporates N-terminal acetylation and C-terminal amidation, modifications commonly applied in peptide chemistry to improve resistance to enzymatic degradation, enhance metabolic stability, and increase blood-brain barrier permeability. These structural features extend the peptide’s biological half-life while preserving the pharmacodynamic profile of its parent molecule. Like Selank, N-Acetyl Selank Amidate is investigated for its modulation of GABAergic neurotransmission, with preclinical data suggesting allosteric activity at GABAA receptors and differential regulation of receptor subunit gene expression. Additional research has identified effects on BDNF expression in the hippocampus, monoamine neurotransmitter metabolism including serotonin and dopamine pathways, and cytokine signaling through IL-6 and T-helper cell regulation. These multi-system interactions position N-Acetyl Selank Amidate as a research tool for investigating neuroimmune modulation, stress adaptation, and peptide-mediated synaptic regulation.
Product Care:
Store in a cool, dry place away from light. If constituted, please refrigerate. For longer term storage, freezing at -20°C is recommended to maintain integrity.
Product Note:
All products are shipped in lyophilized or powder form and must be reconstituted to a liquid for research and testing. All products should be considered research grade. For laboratory use only.